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A Trudell Medical Group Company

More Medication to More of the Nose

Trust the NasoNeb® System to Deliver So You Can Focus On What Matters Most - Your Patients

The NasoNeb® System Advantage

Demonstrated by peer-reviewed clinical data, the NasoNeb® System's advantage derives from the unique combination of the right air flow, fluid volume, and particle size not found in any other device.

The NasoNeb® System delivers a high concentration of medication throughout the nasal and paranasal sinus cavities, unlike squeeze bottles that reach only the front of the nasal cavity.

Filtered air from the system compressor mixes with medication in the NasoNeb cup to create a large droplet spray. The large droplets ensure the medication stays in the nasal cavity and out of the lungs. The airflow pushes the spray deep into the nasal cavity, past those structures that stop weaker nasal sprays delivered by spray bottles. 

Professionals Trust NasoNeb

Allergists
ENT Doctors
Naturopaths
Pharmacists

Plastic Surgeons
Respiratory Therapists
Sleep Therapists

The NasoNeb®'s System delivers medication deep for a superior deposition over irrigation with significant improvement in symptoms and breathing.

Daily Relief for Your Patients Allergy, Asthma, COLD and Flu Symptoms

NasoNeb, Inc.®

Located in Plattsburgh, NY, USA, NasoNeb, Inc. ® is part of the Trudell Medical Group of companies, which share a common vision to provide patients throughout the world with medical devices and services that make their lives better. The Trudell Medical Group companies manufactures and globally markets some of the leading brands in respiratory care, including the AeroChamber® brand of spacers, Aerobika® brand of OPEP devices, and AeroEclipse® brand of nebulizers.

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Clinical Evidence

Journal Articles & Abstracts

Journal Articles & Abstracts

Saline Nasal Irrigation for Upper Respiratory Conditions

Acute and chronic upper respiratory conditions are common and expensive disorders with enormous impact on patient quality of life and society at large. Saline nasal irrigation (SNI), a therapy with roots in Ayurvedic medicine that bathes the nasal mucosa with in spray or liquid saline, has been used as adjunctive care for upper respiratory conditions. In liquid form, SNI has been found to be effective adjunctive care by the Cochrane Collaboration for symptoms associated with chronic rhinosinusitis. Less conclusive clinical trial evidence supports...

Saline nasal irrigations for chronic rhinosinusitis: From everyday practice to evidence-based medicine. An update

Saline nasal irrigations (SNIs) are often recommended as an additional non-pharmacological treatment for adults with chronic rhinosinusitis (CRS), for which it could even be considered a first-line treatment. However, there is a wide range of different SNI protocols. The aim of this article is to review the published literature regarding all of the potential therapeutic effects of SNIs in adult CRS patients who had not undergone sinus surgery and clarify the role of the various saline nasal solutions and protocols...

A Pilot Study of the Effects of Intranasal Budesonide Delivered by NasoNeb® on Patients with Perennial Allergic Rhinitis

We performed a parallel, randomized, double‐blind, placebo‐controlled, pilot study in subjects (n = 40) with perennial allergic rhinitis. After recording baseline symptoms, subjects were randomized to budesonide respules (0.25 mg) or an equivalent placebo for 26 days. Nasal peak inspiratory flow (NPIF) and nasal symptoms (graded on a 0–3 scale) were recorded by the subjects twice daily. Rhinoconjunctivitis quality of life (RQOL) as well as nasal volume, measured by acoustic rhinometry, was obtained at baseline, after 2 weeks, and at the end of treatment.

The effect of Antibiotics on the Microbiome in Acute Exacerbations of Chronic Rhinosinusitis.

Current treatment of acute exacerbations of chronic rhinosinusitis (CRS) is driven by identification of predominant bacteria using culture‐based methods and determination of antibiotic sensitivities. The objective of this study was to evaluate the response of the sinonasal microbiome to antibiotic therapy in the setting of an acute exacerbation of CRS.

Prospective evaluation of aerosol delivery by a powered nasal nebulizer in the cadaver model

The nebulizer consistently delivered aerosolized saline to multiple nasal subsites, with improvement in delivery seen to the middle meatal region after FESS and F-NEO after FESS with EML. This may have important implications for the delivery of topical medications to the paranasal sinuses in the postoperative setting.

Targeted versus Universal Decolonization to Prevent ICU Infection

In routine ICU practice, universal decolonization was more effective than targeted decolonization or screening and isolation in reducing rates of MRSA clinical isolates and bloodstream infection from any pathogen. (Funded by the Agency for Healthcare Research and the Centers for Disease Control and Prevention; REDUCE MRSA ClinicalTrials.gov number, NCT00980980. opens in new tab.)

Journal Articles & Abstracts

Journal Articles & Abstracts

Support for the Moisturizing Solution Ingredients

Beneficial Effects of Propylene and Polyethylene Glycol and Saline in the Treatment of Perennial Rhinitis.

Although propylene-and-polyethylene-glycol and saline have been used in clinical studies as placebos, their possible therapeutic role as wetting agents in the treatment of perennial rhinitis was investigated. Clinical and laboratory response to these agents was measured in eighteen patients during a 2-week baseline period and with 4 weeks of active treatment in a double blind randomized study. After 2 and 4 weeks there was a significant improvement compared to baseline in nasal function...

Bactericidal Activity of Propylene Glycol, Glycerine, Polyethylene Glycol 400, and Polyethylene Glycol 1000 Against Selected Microorganisms

The aim of the present study was to evaluate the bactericidal activity of propylene glycol, glycerine, polyethylene glycol 400 (PEG 400), and polyethylene glycol 1000 (PEG 1000) against selected microorganisms in vitro.

Solubilizing Agents in Nasal Formulations and Their Effect on Ciliary Beat Frequency.

The purpose of this study was to determine the concentration-dependent effect of selected solubilizers, used in common nasal drug formulations, on ciliary beat frequency (CBF) in human nasal epithelial cell cultures. CBF was measured by a high-speed digital imaging method. Excised ciliated human nasal epithelial cells were incubated for 60min with the solubilizers and determination of the half maximal inhibitory concentration (IC(50)), followed by a reversibility test. LDH test was performed on human nasal epithelial cells with the solubilizing agents...

Clinically-shown to reach the whole nasal and paranasal sinus cavities

Source: (1) In-vivo study, Yuri M. Gelfand, MD; Samer Fakhri, MD; Amber Luong, MD, PhD; Seth J. Isaacs, MD & Martin J. Citardi, MD: “A Comparative Study of the Distribution of Normal Saline Delivered by Large Particle Nebulizer vs. Large Volume/Low Pressure Squeeze Bottle” 56th Annual Meeting of the American Rhinologic Society, September 25, 2010, page 38 (2) In-vivo study, Manes RP, Tong L, Batra PS.: “Prospective evaluation of aerosol delivery by a powered nasal nebulizer in the cadaver model” Int Forum Allergy Rhinol, 2011; 1:366–371

See how the NasoNeb® System
stacks up to the Competition

Rinses & Irrigators

Flushes your nasal cavity with saline

Sprays

Squirts solution into the front of your nose

NasoNeb®: The Only Dual Action Experience

The Sinus Therapy System delivers greater than 30x more medication to the entire nasal and paranasal cavities compared to using nasal rinses or small volume nebulizers1, 2.

Gentle
Cleansing

Deeply Moisturize
or Medicate

NasoNeb® Sinus Therapy System

Dual Action: Cleanse + Medicate or Moisturize for improved outcomes

Reaches Sinuses

Deeply delivers high concentrations for increased treatment effectiveness

Quick + Easy to Use, No Mess.

1. Yuri M. Gelfand, MD; Samer Fakhri, MD; Amber Luong, MD, PhD; Seth J. Isaacs, MD & Martin J. Citardi, MD: “A Comparative Study of the Distribution of Normal Saline Delivered by Large Particle Nebulizer vs. Large Volume/Low Pressure Squeeze Bottle” 56th Annual Meeting of the American Rhinologic Society, September 25, 2010, page 38
2. Manes RP, Tong L, Batra PS.: “Prospective evaluation of aerosol delivery by a powered nasal nebulizer in the cadaver model” Int Forum Allergy Rhinol, 2011; 1:366–371 

See how the NasoNeb® System
stacks up to the Competition

Rinses & Irrigators

Flushes your nasal cavity with saline

Sprays

Squirts solution into the front of your nose

NasoNeb®: The Only Dual Action Experience

The Sinus Therapy System delivers greater than 30x more medication to the entire nasal and paranasal cavities compared to using nasal rinses or small volume nebulizers1, 2.

Gentle
Cleansing

Deeply Moisturize
or Medicate

NasoNeb® Sinus Therapy System

Dual Action: Cleanse + Medicate or Moisturize for improved outcomes

Reaches Sinuses

Deeply delivers high concentrations for increased treatment effectiveness

Quick + Easy to Use, No Mess.

1. Yuri M. Gelfand, MD; Samer Fakhri, MD; Amber Luong, MD, PhD; Seth J. Isaacs, MD & Martin J. Citardi, MD: “A Comparative Study of the Distribution of Normal Saline Delivered by Large Particle Nebulizer vs. Large Volume/Low Pressure Squeeze Bottle” 56th Annual Meeting of the American Rhinologic Society, September 25, 2010, page 38
2. Manes RP, Tong L, Batra PS.: “Prospective evaluation of aerosol delivery by a powered nasal nebulizer in the cadaver model” Int Forum Allergy Rhinol, 2011; 1:366–371 

Healthcare - FAQ

FSA & HSA Eligible

All NasoNeb® Products are FSA and HSA eligible so you can use your Flexible Spending & Health Savings Accounts.

Rex Awards 2020: OTC

For it's second year, Drug Store News (DSN) recognizes NasoNeb, Inc. to be at the forefront of innovation to help consumers' be the healthiest they can be!

Rex Awards 2019: OTC

Drug Store News (DSN) featured and awarded the NasoNeb, Inc. for it's unique way of allergy, sinus, cold, and flu relief!

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